Total-body irradiation is indicated for what reason?

Total-body irradiation is indicated for what reason?

a.
Palliative care
b.
Lymphoma therapy
c.
Definitive therapy for leukemia
d.
Preparation for bone marrow transplant

ANS: D

Total-body irradiation is used as part of the destruction of the child’s immune system necessary for a bone marrow transplant. The child is at great risk for complications because there is no supportive therapy until engraftment of the donor marrow takes place. Irradiation for palliative care is done selectively. The area that is causing pain or potential obstruction is irradiated. Lymphoma and leukemia are treated through a combination of modalities. Total-body irradiation is not indicated.